Trabecular microarchitecture in established osteoporosis: relationship between vertebrae, distal radius and calcaneus by X-ray imaging texture analysis

TitreTrabecular microarchitecture in established osteoporosis: relationship between vertebrae, distal radius and calcaneus by X-ray imaging texture analysis
Type de publicationArticle de revue
AuteurMallard, F, Bouvard, Béatrice, Mercier, Philippe, Bizot, Pascal, Cronier, P., Chappard, Daniel
PaysFrance
EditeurElsevier Masson
VilleParis
TypeArticle scientifique dans une revue à comité de lecture
Année2013
LangueAnglais
Date2013 Feb
Numéro1
Pagination52-59
Volume99
Titre de la revueOrthopaedics & Traumatology: Surgery & Research
ISSN1877-0568
Mots-clésAged, 80 and over, Calcaneus, Female, Humans, Male, Radius, Retrospective Studies, Spinal Fractures, Spine
Résumé en anglais

INTRODUCTION: Osteoporosis is an alteration of bone mass and microarchitecture leading to an increased risk of fractures. A radiograph is a 2D projection of the 3D bone network exposing a texture, that can be assessed by texture analysis. We compared the trabecular microarchitecture of the spine, radius and calcaneus in a series of osteoporotic cadavers.

MATERIALS AND METHODS: Thirty-four cadavers (11 men, 23 women), mean age 85.2±2.1years, were radiographed from T4 to L5 to identify those with vertebral fractures (FV). Non-fractured vertebrae (NFV), radius and calcaneus were taken and analyzed by densitometry, radiography and texture analysis under run-length, skeletonization of the trabeculae, and fractal geometry.

RESULTS: Six subjects (five women, one man) were selected, mean age 82.5±5.5years. Twelve calcanei and 10 radii were taken. Two radii were excluded. The texture of NFV was significantly correlated (P<0.01) with that of the radius for horizontal run-lengths. No relationship between the texture of NFV and calcaneus was found.

DISCUSSION: In the horizontal direction (perpendicular to the stress lines), the microarchitecture of NFV and radius showed a disappearance of the transverse rods anchoring the plates. Due to its particular microarchitecture, the calcaneus is not representative of the vertebral status.

CONCLUSION: Bone densitometry provides no information about microarchitecture. Texture analysis of X-ray images of the radius would be a minimally invasive tool, providing an early detection of microarchitectural alterations.

LEVEL OF EVIDENCE: IV retrospective study.

URL de la noticehttp://okina.univ-angers.fr/publications/ua10359
DOI10.1016/j.otsr.2012.08.004
Titre abrégéOrthop Traumatol Surg Res
Identifiant (ID) PubMed23260368