Intraoperative Contrast-Enhanced Ultrasound in Colorectal Liver Metastasis Surgery Improves the Identification and Characterization of Nodules

TitreIntraoperative Contrast-Enhanced Ultrasound in Colorectal Liver Metastasis Surgery Improves the Identification and Characterization of Nodules
Type de publicationArticle de revue
AuteurHoareau, Julien, Venara, Aurélien , Lebigot, Jérôme , Hamel, Jean-François, Lermite, Emilie , Caroli-Bosc, François-Xavier , Aubé, Christophe
EditeurSpringer Verlag
TypeArticle scientifique dans une revue à comité de lecture
Année2016
LangueAnglais
DateJanvier 2016
Numéro1
Pagination190-7
Volume40
Titre de la revueWorld Journal of Surgery
ISSN1432-2323
Mots-clésAdult, Aged, Aged, 80 and over, Colorectal Neoplasms, Contrast Media, Digestive System Surgical Procedures, Female, Follow-Up Studies, Humans, Intraoperative Care, Liver neoplasms, Magnetic Resonance Imaging, Male, Middle Aged, Predictive Value of Tests, Preoperative Care, Sensitivity and Specificity, Ultrasonography, Interventional
Résumé en anglais

INTRODUCTION: The sensitivity of preoperative assessment of colorectal liver metastases (CRLM) ranges from 74 to 80%. Intraoperative ultrasound (IOUS) associated with contrast-enhanced intraoperative ultrasound (CE-IOUS) may be able to improve this. Thus, the aims of this study were to assess the value of IOUS and CE-IOUS for the surgical approach and to determine risk factors both for the detection of new nodules and for the modification of the surgical strategy.

MATERIALS AND METHODS: Forty-three patients who underwent CRLM surgery were included. These patients had an MRI in the 8 weeks preceding surgery and benefited from intraoperative IOUS and CE-IOUS.

RESULTS AND DISCUSSION: The use of IOUS/CE-IOUS permitted the identification of 43 additional lesions and an improved characterization of nodules in 23 patients with a resulting modification of surgical strategy. Lesions were down-staged in six patients and up-staged in six patients. Chemotherapy (p = 0.02) and the presence of nodules in the left lobe (p = 0.04) were predictive factors for finding new nodules at IOUS/CE-IOUS. The discovery of a new nodule systematically modified surgical management. IOUS/CE-IOUS improved intraoperative management of liver metastases. The techniques enable pertinent modification of surgical resections and a reduction of residual lesions.

URL de la noticehttp://okina.univ-angers.fr/publications/ua18977
DOI10.1007/s00268-015-3269-0
Lien vers le document

https://link.springer.com/article/10.1007%2Fs00268-015-3269-0

Titre abrégéWorld J Surg
Identifiant (ID) PubMed26470698