Échographie de contraste temps réel dans la prise en charge diagnostique des lésions nodulaires hépatiques : évaluation des performances diagnostiques et de l’impact économique sur une étude multicentrique française

TitreÉchographie de contraste temps réel dans la prise en charge diagnostique des lésions nodulaires hépatiques : évaluation des performances diagnostiques et de l’impact économique sur une étude multicentrique française
Type de publicationArticle de revue
AuteurTranquard, F., Correas, Jean-Michel, V. Marcus, Ladam, Manzoni, Philippe, Vilgrain, Valérie, Aubé, Christophe , Elmaleh, A., Chami, L., Claudon, M., Cuilleron, M., Diris, B., Garibaldi, F., Lucidarme, Olivier, Marion, D., Beziat, C., Rode, Agnès, Tasu, Jean-Pierre, Trillaud, Hervé, Bleuzen, Aurore, Le Gouge, Amélie, Giraudeau, Bruno, Rusch, E.
EditeurElsevier Masson
TypeArticle scientifique dans une revue à comité de lecture
Année2009
LangueFrançais
Date2009/01
Numéro1
Pagination109 - 122
Volume90
Titre de la revueJournal de Radiologie
ISSN02210363
Résumé en anglais

The recent introduction of high-end ultrasound equipment combined with recent contrast agents provides marked improvements in the characterization of focal liver lesions as previously reported by monocentric studies. The aim of the present study was to evaluate the diagnostic performance of Contrast-Enhanced Ultrasonography (CEUS) using SonoVue as well as its medico-economic value for characterization of focal liver lesions. These nodules were not characterized on previous CT or conventional sonography. This prospective multicentric study conducted in 15 French centres found diagnostic performances similar to those reported for CT and MRI, with a concordance rate of 84.5%, sensitivity greater than 80% and specificity greater than 90% for all types of lesions. Higher acceptance was found for CEUS compared to other imaging modalities. Economical assessment based on examination reimbursment and contrast agent cost showed a lower cost for contrast ultrasound versus CT and MRI. This French multicentric study confirmed the high diagnostic value of CEUS for focal liver lesion characterization and demonstrated a lower economical impact compared to other imaging modalities such as CT and MRI.

URL de la noticehttp://okina.univ-angers.fr/publications/ua3594
DOI10.1016/S0221-0363(09)70089-7
Lien vers le document

http://dx.doi.org/10.1016/S0221-0363(09)70089-7