Guillain-Barré syndrome during childhood: particular clinical and electrophysiological features

TitreGuillain-Barré syndrome during childhood: particular clinical and electrophysiological features
Type de publicationArticle de revue
AuteurDevos, D., Magot, Armelle, Perrier-Boeswillwald, J., Fayet, G., Leclair-Visonneau, L., Ollivier, Y., Nguyen The Tich, Sylvie , Pereon, Y., Dinomais, Mickaël , Veaux, Fabienne, Richard, Isabelle
EditeurWiley
TypeArticle scientifique dans une revue à comité de lecture
Année2013
LangueAnglais
Numéro2
Pagination247-251
Volume48
Titre de la revueMuscle and Nerve
ISSN0148-639X
Résumé en anglais

Introduction

Guillain–Barré syndrome (GBS) has some specific characteristics in children.

Methods

In this study we reviewed the clinical, laboratory, electrophysiological, and prognosis features of the 19 children diagnosed with GBS at Nantes University Hospital from 2000 to 2011.

Results

Gait disturbance and leg pain were the most frequent presenting symptoms. Electrophysiological examinations revealed significant abnormalities even when performed within the first week after onset. Decreased distal CMAP amplitude was noted in 89% of cases. The pattern indicated an acute inflammatory demyelinating polyneuropathy in 95% of cases and acute motor axonal neuropathy in the remaining 5%. About two-thirds of the children were treated with intravenous immunoglobulin. After >1 year of follow-up, 17 patients had complete recovery.

Conclusion

Gait disorder, leg pain, a high rate of distal conduction block, and a good prognosis are among the main specific features of GBS in childhood. Muscle Nerve, 48: 247–251, 2013

URL de la noticehttp://okina.univ-angers.fr/publications/ua6506
DOI10.1002/mus.23749
Lien vers le document

http://dx.doi.org/10.1002/mus.23749