Quality of life and functional outcome in early school-aged children after neonatal stroke: A prospective cohort study

TitreQuality of life and functional outcome in early school-aged children after neonatal stroke: A prospective cohort study
Type de publicationArticle de revue
AuteurDarteyre, S., Renaud, C., Vuillerot, Carole, Presles, Emilie, Kossorotoff, Manoëlle, Dinomais, Mickaël , Lazaro, L., Gautheron, Vincent, Chabrier, Stéphane
EditeurElsevier
TypeArticle scientifique dans une revue à comité de lecture
Année2014
LangueAnglais
Date05/2014
Numéro3
Pagination347-353
Volume18
Titre de la revueEuropean Journal of Paediatric Neurology
ISSN1090-3798
Résumé en anglais

Background

Quality of life (QoL) is recognized internationally as an efficient tool for evaluating health interventions. To our knowledge, QoL has not been specifically assessed in children after neonatal arterial ischemic stroke (AIS).

Aim

To study the QoL of early school-aged children who suffered from neonatal AIS, and QoL correlation to functional outcome.

Method

We conducted a multicenter prospective cohort study as part of a larger study in full-term newborns with symptomatic AIS. Participating families were sent anonymous QoL questionnaires (QUALIN). Functional outcome was measured using the Wee-FIM scale. Healthy controls in the same age range were recruited in public schools. Their primary caregivers filled in the QUALIN questionnaires anonymously. We used Student's t-test and a rank test to compare patients and controls' QoL and functional outcomes.

Results

84 children with neonatal AIS were included. The control group was composed of 74 children, of which ten were later excluded due to chronic conditions. Mean ages and QUALIN median scores did not differ between patients and controls. Median Wee-FIM scores were lower in hemiplegic children than in non-hemiplegic ones (p < 0.001). QoL scores did not seem correlated to functional outcome.

Interpretation

Those results could support the presence of a “disability paradox” in young children following neonatal AIS.

URL de la noticehttp://okina.univ-angers.fr/publications/ua6761
DOI10.1016/j.ejpn.2014.01.006
Lien vers le document

http://dx.doi.org/10.1016/j.ejpn.2014.01.006