Titre | High throughput screening for identification of mycolactone targets : Relations between M. ulcerans and nervous system |
Type de publication | Communication |
Type | Communication sans actes dans un congrès |
Année | 2010 |
Langue | Anglais |
Date du colloque | 22-24/03/2010 |
Titre du colloque | 13th annual meeting on Buruli ulcer |
Pagination | 192 |
Auteur | Marion, Estelle , Marsollier, Laurent , Song, Ok-Ryul , Cassisa, Viviane , Letournel, Franck, Dantec, C. , Legras, Pierre , Brodin, Priscille |
Pays | Suisse |
Editeur | World Health Organization |
Ville | Genève |
Résumé en anglais | Buruli ulcer is an infectious disease transmitted by arthropod vectors harboring Mycobacterium ulcerans, a mycobacterium which belong to the same family of bacteria causing tuberculosis and leprosy. The infection causes painless swelling and severe skin lesions. One key feature of M. ulcerans bacterium is its ability to secrete a necrotic toxin, the mycolactone within small lipophilic vesicles, which are critical for the bacterial induced cytotoxicity. The biological knowledge as well as the preventive and therapeutic means for this invalidating disease is still very limited. |
URL de la notice | http://okina.univ-angers.fr/publications/ua11305 |
Lien vers le document en ligne | http://www.who.int/buruli/information/Buruli_Meeting_2010_Abstracts_ENG.pdf |