A semi-automated method for measuring the evolution of both lumen area and blood flow in carotid from Phase Contrast MRI

TitreA semi-automated method for measuring the evolution of both lumen area and blood flow in carotid from Phase Contrast MRI
Type de publicationArticle de revue
AuteurFasquel, Jean-Baptiste , Lécluse, Aldéric, Cavaro-Ménard, Christine , Willoteaux, Serge
EditeurElsevier
TypeArticle scientifique dans une revue à comité de lecture
Année2015
LangueAnglais
Date1er Nov. 2015
Pagination269-277
Volume66
Titre de la revueComputers in Biology and Medicine
ISSN0010-4825
Mots-clésMagnetic Resonance Imaging, Phantom, r Blood flow, Region-based active contou, Semi-automated analysis
Résumé en anglais

Phase-Contrast (PC) velocimetry Magnetic Resonance Imaging (MRI) is a useful modality to explore cardiovascular pathologies, but requires the automatic segmentation of vessels and the measurement of both lumen area and blood flow evolutions. In this paper, we propose a semi-automated method for extracting lumen boundaries of the carotid artery and compute both lumen area and blood flow evolutions over the cardiac cycle. This method uses narrow band region-based active contours in order to correctly capture the lumen boundary without being corrupted by surrounding structures. This approach is compared to traditional edge-based active contours, considered in related works, which significantly underestimate lumen area and blood flow. Experiments are performed using both a sequence of a homemade phantom and sequences of 20 real carotids, including a comparison with manual segmentation performed by a radiologist expert. Results obtained on the phantom sequence show that the edge-based approach leads to an underestimate of carotid lumen area and related flows of respectively 18.68% and 4.95%. This appears significantly larger than weak errors obtained using the region-based approach (respectively 2.73% and 1.23%). Benefits appear even better on the real sequences. The edge-based approach leads to underestimates of 40.88% for areas and 13.39% for blood flows, compared to limited errors of 7.41% and 4.6% with our method. Experiments also illustrate the high variability and therefore the lack of reliability of manual segmentation.

URL de la noticehttp://okina.univ-angers.fr/publications/ua17086
DOI10.1016/j.compbiomed.2015.09.017
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