A Novel FibroScan Examination Dedicated to Spleen Stiffness Measurement.

TitreA Novel FibroScan Examination Dedicated to Spleen Stiffness Measurement.
Type de publicationArticle de revue
AuteurBastard, Cécile, Miette, Véronique, Calès, Paul , Stefanescu, Horia, Festi, Davide, Sandrin, Laurent
TypeArticle scientifique dans une revue à comité de lecture
DateAoût 2018
Titre de la revueUltrasound Med Biol
Mots-clésAdult, Aged, Animals, Elasticity Imaging Techniques, Esophageal and Gastric Varices, Female, Humans, Image Processing, Computer-Assisted, Male, Middle Aged, Reproducibility of Results, Severity of Illness Index, Spleen
Résumé en anglais

Esophageal varices (EVs) are among the most severe complications of cirrhosis, with a prevalence of 50% to 60% among cirrhotic patients. International guidelines therefore recommend that cirrhotic patients should be screened for the presence of EVs. The main objective of this study was to introduce a new spleen-dedicated FibroScan (Echosens, Paris, France) examination and to assess its performance in detecting large EVs (grade 2 and 3). This novel examination has been validated in simulation and phantom studies and has been used in a population of patients with chronic liver disease. The study described here suggests that the novel spleen-dedicated FibroScan examination performs better than the standard FibroScan for the detection of large EVs (area under the curve = 0.70 for the standard examination and 0.79 [p <0.01] for the spleen examination), but further clinical studies are needed to investigate the role of spleen stiffness in the management of cirrhotic patients.

URL de la noticehttp://okina.univ-angers.fr/publications/ua18741
Lien vers le document


Autre titreUltrasound Med Biol
Identifiant (ID) PubMed29731186