Rigidité artérielle mesurée par pOpmètre® chez les patients à risque cardiovasculaire, lien aux plaques d’athérome carotidien

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TitreRigidité artérielle mesurée par pOpmètre® chez les patients à risque cardiovasculaire, lien aux plaques d’athérome carotidien
Type de publicationArticle de revue
AuteurHallab, Magid, Collette, Mathieu
1, 2
, Terrier-Barbeau, C., Legrand, Mathieu , Ducluzeau-Fieloux, Pierre-Henri, Berrut, Gilles, Lefthériotis, Georges
EditeurElsevier Masson
TypeArticle scientifique dans une revue à comité de lecture
Année2013
LangueAnglais
DateJan-06-2013
Numéro3
Pagination189-192
Volume62
Titre de la revueAnnales de Cardiologie et d'Angéiologie
ISSN0003-3928
Mots-clésAtherosclerotic/pathology/physiopathology/ultrasonography, Cardiovascular Diseases/prevention & control, Carotid Intima-Media Thickness, Carotid Stenosis/pathology/physiopathology/ultrasonography, Female, Fingers, Humans, Male, Manometry/instrumentation, Middle Aged, Plaque, Pulse Wave Analysis, Risk Factors, Toes, Vascular Stiffness
Résumé en anglais

PURPOSE:

Aortic stiffness is a functional and structural consequence of ageing and arteriosclerosis. Regional arterial stiffness can be easily evaluated using pOpmetre(®) (Axelife SAS, France). This new technique assesses the pulse wave transit time (TT) between the finger (TTf) and the toe (TTt). Based on height chart, regional pulse wave velocity (PWV) between the toe and the finger can be estimated (PWVtf). pOpscore(®) index is also calculated as the ratio between PWVtoe and PWVfinger and can be considered as a peripheral vascular stiffness index. The aim of the study was to evaluate the relationship between pOpmetre(®) indices and the presence of carotid plaques in a population with cardiovascular risk factors.

METHODS:

In 77 consecutive patients recruited for a vascular screening for atherosclerosis (46 men aged 54 ± 2 years; 31 women aged 49 ± 3 years; ns), the difference between TTt and TTf (called Dt-f), the regional pulse wave velocity between the toe and the finger (PWVtf = constant × height/Dt-fm/s) and pOpscore(®) were measured by pOpmetre(®). Presence of carotid plaques was assessed using ultrasound imaging. The local aortic stiffness (AoStiff) was evaluated by the Physioflow(®) system.

RESULTS:

No difference was found between patients with or without carotid plaques (n=25 versus 52) for Ankle-Brachial Pressure Index (ABPI: 1.15 ± 0.04 versus 1.12 ± 0.03), nor for diastolic or systolic blood pressure (87 ± 3 versus 82 ± 2; 137 ± 3 versus 132 ± 2 mmHg). The first group was older than the second (59 ± 2 versus 49 ± 2 years, P<0.002) with a larger intimae media thickness (0.69 ± 0.02 versus 0.63 ± 0.01 mm, P<0.004), a higher AoStiff (10.4 ± 0.7 versus 8.2 ± 0.5m/s, P<0.02), and PWVtf (14.3 ± 1.0 versus 10.7 ± 0.7 m/s, P<0.004) and a shorter Dt-f (57.9 ± 5.1 versus 73.5 ± 3.5 ms, P<0.01). PWVtf (r(2)=0.49, P<0.0001) and Dt-f (r(2)=0.54, P<0.0001) correlated with age. A significant difference in pOpscore(®) index was observed between both groups (1.51 ± 0.3 versus 1.41 ± 0.2, P<0.006).

CONCLUSION:

Our results show a significant arterial stiffness indices measured by pOpmetre(®) in patients with and without carotid plaques.

URL de la noticehttp://okina.univ-angers.fr/publications/ua3405
DOI10.1016/j.ancard.2013.04.001
Lien vers le document

http://dx.doi.org/10.1016/j.ancard.2013.04.001

Titre abrégéAnn Cardiol Angeiol