Synthesis, crystal structure, characterization of zinc(II), cadmium(II) complexes with 3-thiophene aldehyde thiosemicarbazone (3TTSCH). Biological activities of 3TTSCH and its complexes

TitreSynthesis, crystal structure, characterization of zinc(II), cadmium(II) complexes with 3-thiophene aldehyde thiosemicarbazone (3TTSCH). Biological activities of 3TTSCH and its complexes
Type de publicationArticle de revue
AuteurAlomar, Kusaï, Landreau, Anne , Kempf, Marie , Khan, Mustayeen Ahmed , Allain, Magali , Bouet, Gilles
EditeurElsevier
TypeArticle scientifique dans une revue à comité de lecture
Année2010
LangueAnglais
Date2010/04
Numéro4
Pagination397 - 404
Volume104
Titre de la revueJournal of Inorganic Biochemistry
ISSN0162-0134
Mots-clés3-Thiophene aldehyde, Biological activity, Crystal structure, Metal complexes, Thiosemicarbazone
Résumé en anglais

The reaction of zinc(II) chloride, cadmium(II) chloride and bromide with 3-thiophene aldehyde thiosemicarbazone leads to the formation of a series of new complexes. They have been characterized by spectroscopic studies: infrared, 1H NMR, and electronic spectra. The crystal structures of the compound [ZnCl2(3TTSCH)2] and [CdBr2(3TTSCH)2] have been determined by X-ray diffraction methods. For the complexes [ZnCl2(3TTSCH)2] and [CdBr2(3TTSCH)2], the central ion is coordinated through the sulfur, and for the complexes [CdCl2(3TTSCH)], [CdBr2(3TTSCH)] the ion is coordinated through the sulfur as well as azomethine nitrogen atom of the thiosemicarbazone. In addition, fungistatic and bacteriostatic activities of both ligand and complexes have been evaluated. Cadmium(II) complexes have shown the most significant activities.

URL de la noticehttp://okina.univ-angers.fr/publications/ua57
DOI10.1016/j.jinorgbio.2009.11.012
Lien vers le document

http://dx.doi.org/10.1016/j.jinorgbio.2009.11.012