Anti-ages activity screening of molecules isolated from Tanzanian clusiaceous species

TitreAnti-ages activity screening of molecules isolated from Tanzanian clusiaceous species
Type de publicationCommunication
TypeCommunication par affiche dans un congrès
Année2012
Date du colloque2012/07/19
Titre du colloqueInternational Congress on Natural Products Research on Global Change, Natural Products and Human Health/8th Joint Meeting of AFERP, ASP, GA, PSE and SIF
Numéro11
Volume78
Pagination1227 - 1228
AuteurMagadula, J. J, Julia, Gatto , Mbwambo, Z. H, Derbré, Séverine , Guilet, David , Richomme, Pascal
PaysEtats-Unis
EditeurPlanta Medica
VilleNew-York
Résumé en anglais

Advanced glycation end-products (AGEs) are involved in the progression of numerous pathologies such as diabetes or atherosclerosis. With the objective of finding molecules with inhibitory effects on AGEs formation, we have conducted a phytochemical investigation on three Tanzanian Clusiaceous species: Garcinia semseii, Garcinia volkensii and Allanblackia uluguruensis. Several polyphenolic compounds exhibiting phloroglucinol moieties [e.g. polyprenylated benzophenones, such as guttiferone F (1) or biflavonoïds, such as morelloflavone (2)] were identified and their anti-AGEs activities were evaluated using a recently developed automated assay.

URL de la noticehttp://okina.univ-angers.fr/publications/ua7
DOI10.1055/s-0032-1321060
Lien vers le document en ligne

http://dx.doi.org/10.1055/s-0032-1321060